Table 3 Associations of greater treatment burden and greater multimorbidity
From: The burden of comorbidity in people with chronic kidney disease stage 3: a cohort study
Variable | More than five medications per day | Three or more comorbidities | |||||||
|---|---|---|---|---|---|---|---|---|---|
(vs. five or fewer) | (vs. two or fewer) | ||||||||
Univariate | Multivariablea | Univariate | Multivariablea | ||||||
OR (95Â % CI) | p value | OR (95Â % CI) | p value | OR (95Â % CI) | p value | OR (95Â % CI) | p value | ||
Age (years) | 1.05 (1.03–1.06) | <0.001 | 1.04 (1.03–1.06) | <0.001 | 1.04 (1.02–1.05) | <0.001 | 1.03 (1.02–1.05) | <0.001 | |
Sex (male vs. female) | 1.26 (1.03–1.53) | 0.02 | 1.14 (0.92–1.43) | 0.231 | 1.25 (1.03–1.52) | 0.027 | 1.09 (0.88–1.36) | 0.434 | |
Education status (vs. highest level of qualifications) | Group1 (No formal qualifications) | 1.83 (1.41–2.36) | <0.001 | 1.44 (1.10–1.90) | 0.01 | 1.38 (1.06–1.79) | 0.035 | 1.14 (0.86–1.52) | 0.361 |
Group 2 (GCSE, A level, NVQ1-3) | 1.29 (0.97–1.72) | 1.27 (0.94–1.73) | 1.14 (0.85–1.53) | 1.13 (0.82–1.55) | |||||
Smoking (vs. non smokers) | Current smoker | 1.02 (0.64–1.61) | <0.001 | 1.49 (0.91–2.44) | <0.001 | 1.02 (0.63–1.65) | <0.001 | 1.38 (0.83–2.28) | <0.001 |
Ex smoker | 1.57 (1.29–1.92) | 1.45 (1.18–1.79) | 1.68 (1.38–2.05) | 1.54 (1.25–1.91) | |||||
BMI (kg/m2, continuous) | 1.08 (1.05–1.10) | <0.001 | 1.09 (1.07–1.11) | <0.001 | 1.06 (1.04–1.08) | <0.001 | 1.07 (1.05–1.10) | <0.001 | |
eGFR (ml/min per 1.73 m2, continuous) | 0.96 (0.95–0.97) | <0.001 | 0.97 (0.96–0.98) | <0.001 | 0.97 (0.96–0.98) | <0.001 | 0.97 (0.96–0.98) | <0.001 | |
Log average uACR (mg/mmol, continuous) | 1.00 (1.00–1.00) | 0.70 | - | - | 1.00 (0.99–1.00) | 0.384 | - | - | |