Table 1 Effect of PDTC on the percentage of viable HK-2, WT9-7 and WT9-12 cells, assessed by MTT assay after 6 h, 24 h and 48 h of treatment
HK-2 | WT9-7 | WT9-12 | |
|---|---|---|---|
6 h | |||
Control | 100 ± 19.0 | 100 ± 10.2 | 100 ± 13.9 |
5 μM | 99.6 ± 8.5 | 110 ± 26.8 | 103.0 ± 9.8 |
20 μM | 98.8 ± 9.2 | 120.2 ± 13.1 | 97.1 ± 7.8 |
50 μM | 76.8 ± 13.5 | 43.4 ± 9.3 ** | 87.6 ± 14.1 |
24 h | |||
Control | 100 ± 15.0 | 100 ± 8.8 | 100 ± 12.6 |
5 μM | 105.8 ± 7.7 | 85.2 ± 20.1 | 97.8 ± 14.3 |
20 μM | 112.2 ± 7.6 | 103.6 ± 27.3 | 99.9 ± 9.1 |
50 μM | 42.7 ± 2.8 ** | 17.1 ± 7.7 ** | 72.9 ± 5.9 ** |
48 h | |||
Control | 100 ± 9.6 | 100 ± 13.3 | 100 ± 5.9 |
5 μM | 76.9 ± 7.1 ** | 50.4 ± 11.7 ** | 75.9 ± 8.4 ** |
20 μM | 90.3 ± 10.9 | 91.7 ± 24.0 | 82.1 ± 8.0 ** |
50 μM | 19.3 ± 2.0 ** | 6.0 ± 0.5 ** | 51.7 ± 9.2 ** |