From: Low dose of mycophenolate mofetil is enough in desensitized kidney transplantation using rituximab
Low dose MMF | Conventional dose MMF | p1a | p2b | ||
---|---|---|---|---|---|
Rituximab(+) | Rituximab(+) | Rituximab(−) | |||
Group 1 (n = 72) | Group 2 (n = 67) | Group 3 (n = 87) | |||
Incidence of infection | 12 (16.7 %) | 25 (37.3 %) | 30 (34.5 %) | 0.007 | 0.012 |
Cytomegalovirus | 2 (2.8 %) | 11 (16.4 %) | 5 (5.7 %) | 0.007 | 0.458 |
BK virus | 6 (8.3 %) | 9 (13.4 %) | 11 (12.6 %) | 0.416 | 0.447 |
Urinary tract infection | 5 (6.9 %) | 6 (9.0 %) | 14 (16.1 %) | 0.758 | 0.090 |
Pneumonia | 1 (1.4 %) | 6 (9.0 %) | 4 (4.6 %) | 0.056 | 0.378 |
Sepsis | 0 (0.0 %) | 4 (6.0 %) | 2 (2.3 %) | 0.051 | 0.501 |