Risk factors | Renal dysfunction° Tromsø 5 2001/02 (n = 474) | p-value | ACR ≥ 1.13 mg/mmol Tromsø 5 2001/02 (n = 394) | p- value | Estimated GFR <60 ml/min/1.73 m2 Tromsø 5, 2001/02 (n = 117) | p- value |
---|---|---|---|---|---|---|
Age, per 5 years increase | 1.13 (1.02, 1.25) | 0.02 | 1.19 (1.06, 1.33) | 0.002 | 1.44 (1.15, 1.80) | <0.001 |
SUA increasersa | 1.98 (1.52, 2.59) | <0.001 | 1.35 (1.018, 1.82) | 0.044 | 4.85 (2.87, 8.19) | <0.001 |
Baseline SUA, per 59 μmol/L (1 mg/dl) increase | 1.10 (0.99, 1.24) | 0.09 | 1.05 (0.92, 1.18) | 0.5 | 1.42 (1.15, 1.75) | 0.001 |
Estimated GFR per 5 ml/1.73 m2 decrease | 1.22 (1.17, 1.27) | <0.001 | 1.05 (0.99, 1.12) | 0.16 | 1.44 (1.38, 1.49) | <0.001 |
Log ACR per unit | 26.9 (18.3, 39.7) | <0.001 | 44.87 (29.57, 68.08) | <0.001 | 1.47 (0.86, 2.49) | 0.16 |
Renal dysfunction Tromsø 6 2007/08 (n = 697) | ACR ≥ 1.13 mg/mmol Tromsø 6 2007/08 (n = 589) | Estimated GFR < 60 ml/min/1.73 m2 Tromsø 6, 2007/08 (n = 220) | ||||
Age, per 5 years increase | 1.27 (1.17, 1.38) | <0.001 | 1.31 (1.19, 1.43) | <0.001 | 1.65 (1.39, 1.94) | <0.001 |
SUA increasersa | 2.12 (1.71, 2.65) | <0.001 | 1.46 (1.16, 1.85) | <0.001 | 5.11 (3.45, 7,56) | <0.001 |
Baseline SUA, per 59 μmol/L (1 mg/dl) increase | 1.15 (1.05, 1.26) | 0.003 | 1.09 (0.99, 1.21) | 0.09 | 1.35 (1.16, 1.58) | <0.001 |
Estimated GFR per 5 ml/1.73 m2 decrease | 1.11 (1.06, 1.16) | <0.001 | 0.98 (0.92, 1.03) | 0.5 | 1.38 (1.33, 1.43) | <0.001 |
Log ACR per unit | 6.99 (5.16, 9.48) | <0.001 | 11.11(8.05, 15.32) | <0.001 | 1.60 (1.06, 2.41) | 0.03 |