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Table 1 Examples of abnormal test results affecting AKI diagnosis or management

From: Excessive diagnostic testing in acute kidney injury

Abnormal Test

Examples of Affecting AKI Diagnosis or Management

Urine and Blood Tests

U Eos

• Subsequent diagnosis of acute interstitial nephritis

• Renal biopsy to evaluate for interstitial nephritis

• Withdrawal of offending medication for interstitial nephritis

• Treatment with glucocorticoids

SPEP and SFLCs

• Subsequent diagnosis of multiple myeloma, Waldenstrom’s Macroglobulinemia, or other paraprotein-related disorder involving the kidneys

• Additional testing such as renal biopsy, bone marrow biopsy, or skeletal survey

• Treatment with intravenous fluids, glucocorticoids, or chemotherapy

ANCA

• Subsequent diagnosis of ANCA vasculitis involving the kidneys

• Additional testing such as renal biopsy or skin biopsy

• Treatment with glucocorticoids, cyclophosphamide, rituximab, or plasmapheresis

Cryo

• Subsequent diagnosis of cryoglobulinemia involving the kidneys

• Additional testing such as renal biopsy

• Treatment with glucocorticoids, cyclophosphamide, rituximab, or plasmapheresis

Radiology Tests

 

Renal ultrasound and CTAP

• Placement of a foley catheter

• Placement of a percutaneous nephrostomy tube

• Ureteral stone removal

• Ureteral stent placement

  1. Abbreviations: U Eos urinary eosinophils, SPEP serum protein electrophoresis, SFLCs serum free light chains, ANCA anti-neutrophil cytoplasmic antibody, Cryo cryoglobulins, CTAP computerized tomography of the abdomen and pelvis