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Table 3 Study measurements by visit

From: KNOW-Ped CKD (KoreaN cohort study for outcomes in patients with pediatric CKD): Design and methods

 

Parameter

Screening

Baseline

1 y

2 y

3 y

4 y

5 y

6 y

7 y

8 y

9 y

10 y

General

Informed consent

O

           

Demographic information

O

           

Medical history

O

           

KNHANES questionnaire

 

O

          

Recent events

  

O

O

O

O

O

O

O

O

O

O

Medications

 

O

O

O

O

O

O

O

O

O

O

O

Kidney

CBC, blood/urine chemistry

 

O

O

O

O

O

O

O

O

O

O

O

Kidney ultrasonographya

 

O

O

O

O

O

O

O

O

O

O

O

Isotopic GFR (optional)

 

O

  

O

  

O

  

O

 

Growth

Height, weight, waist/hip ratio, Tanner stage

O

O

O

O

O

O

O

O

O

O

O

Bone age

 

O

O

O

O

O

O

O

O

O

O

O

Cardio-vascular

Blood pressure

 

O

O

O

O

O

O

O

O

O

O

O

Electrocardiogram, chest X-ray

O

 

O

 

O

 

O

 

O

 

O

Echocardiography

 

O

    

O

    

O

24-hour ambulatory blood pressure monitoring (optional)

O

O

 

O

 

O

 

O

 

O

 

Metabolic bone disease

Parathyroid hormone, vitamin D

O

O

 

O

 

O

 

O

 

O

 

Bone mineral density

 

O

    

O

    

O

Neuro-cognitive

Pediatric quality of life

 

O

  

O

  

O

  

O

O

IQ testb

  

O

  

O

  

O

  

O

Behavioral assessmentc

   

O

  

O

  

O

  

Parental bonding instrumentd

 

O

         

O

Bio-repository

Genetic sample

 

O

          

Serum/urine sample

 

O

O

O

O

O

O

O

O

O

O

O

  1. aKidney ultrasonography is performed annually for patients with CAKUT and every 3 years for other patients
  2. bKEDI-WISC (5–15 years) or K-WAIS (16 years or older) [33]. cChild Behavioral Checklist (CBCL) [34], ADHD Rating Scale-IV [35], State-Trait Anxiety Inventory (STAI) [36], and Children’s Depression Inventory (CDI) [37]. dParental bonding instrument [38]
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BMC Nephrology

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