Table 2 Demographic data of included patients, stratified according to the abbreviated REIN score
Abbreviated REIN score | ≤4 n = 1523 | 5–6 n = 619 | 7–8 n = 338 | ≥9 n = 199 | p-value | |
|---|---|---|---|---|---|---|
Screa at start (mg/dl) | 7.2 ± 3.1 | 6.3 ± 2.7 | 6.4 ± 4.5 | 5.9 ± 3.1 | <0.001 | |
Weight (kg) | 71.6 ± 15.7 | 71.6 ± 14.5 | 69.8 ± 14.5 | 69.3 ± 16.1 | 0.18 | |
Height (cm) | 166.5 ± 9.3 | 166.0 ± 8.1 | 168.5 ± 9.3 | 166.6 ± 9.1 | 0.21 | |
Age at start (years) | 64.0 ± 15.2 | 71.7 ± 11.0 | 77.5 ± 10.8 | 67.8 ± 14.3 | <0.001 | |
Female (%) | 48.1 | 38.6 | 34.6 | 32.7 | <0.001 | |
Heart Failure | Stage 0–1 | 70.7 | 34.4 | 16.9 | 8.5 | <0.001 |
Stage 2 | 13.3 | 16.2 | 19.5 | 9.5 | ||
Stage 3 | 13.4 | 23.7 | 34.0 | 62.3 | ||
Stage 4 | 2.1 | 19.7 | 12.7 | 17.6 | ||
Angina Pectoris | None | 86.6 | 66.2 | 61.2 | 54.3 | <0.001 |
Grade 1 | 7.4 | 14.1 | 16.0 | 16.1 | ||
Grade 2 | 4.1 | 9.9 | 9.5 | 8.0 | ||
Grade 3 | 1.4 | 6.9 | 10.1 | 14.6 | ||
Peripheral Vascular Disease | <0.001 | |||||
None | 87.2 | 71.9 | 70.4 | 61.3 | ||
Claudicatio | 8.1 | 15.2 | 15.7 | 17.6 | ||
Resting ischemia | 1.4 | 3.6 | 3.8 | 7.0 | ||
Necrosis/amputation | 3.2 | 9.4 | 10.1 | 14.1 | ||
COPD | None | 83.2 | 71.1 | 66.0 | 59.8 | <0.001 |
Mild | 9.8 | 17.4 | 19.5 | 18.1 | ||
Moderate | 5.6 | 8.6 | 9.8 | 14.1 | ||
Severe | 1.4 | 2.9 | 4.7 | 8.0 | ||
Myocardial Infarction | 11 | 25.5 | 27.8 | 33.2 | <0.001 | |
Percutaneous Coronary Intervention | 13 | 22.6 | 25.7 | 25.6 | <0.001 | |
Arrhythmia | 6.4 | 18.4 | 28.7 | 44.2 | <0.001 | |
Diabetes | 30.2 | 39.7 | 37.3 | 34.7 | <0.001 | |
Diabetic nephropathy | 23 | 26.8 | 24.0 | 23.6 | 0.3 | |
CerebroVascular Disease | 8.7 | 8.7 | 13.7 | 15.0 | <0.001 | |
Dementia | 0.7 | 2.4 | 7.4 | 8.5 | <0.001 | |
Liver disease | 4.7 | 4.2 | 4.0 | 6.5 | <0.001 | |
Left ventricular Hypertrophy | 49.5 | 51.5 | 51.2 | 54.8 | 0.6 | |
Cancer | 8.5 | 19.1 | 29.9 | 34.7 | 0.2 | |
Nutritional status | Normal | 92 | 75.4 | 60.9 | 49.2 | <0.001 |
Malnutrition | 7.4 | 20.2 | 31.7 | 37.7 | ||
Severe malnutrition | 0.6 | 4.4 | 13.1 | 13.1 | ||
Albumin (g/l) | <25 | 0 | 18.3 | 27.2 | 45.2 | <0.001 |
25–30 | 5.6 | 18.3 | 27.5 | 31.2 | ||
30–35 | 19.2 | 33.4 | 30.5 | 22.1 | ||
35–40 | 49.6 | 22.0 | 9.8 | 1.0 | ||
>40 | 25.6 | 8.1 | 5.0 | 0.5 | ||
C-reactive protein (mg/L) | <15 | 73.3 | 54.1 | 44.1 | 40.7 | <0.001 |
15–60 | 20.1 | 29.4 | 35.2 | 33.7 | ||
>60 | 6.6 | 16.5 | 20.7 | 25.6 | ||
Renal Replacement Therapy | <0.001 | |||||
Hospital HD | 77.7 | 80.9 | 85.8 | 88.4 | ||
Satellite HD | 9.5 | 12.1 | 6.5 | 6.5 | ||
PD | 12.8 | 6.9 | 7.7 | 4.5 | ||