Table 1 Comparisons of the clinical features between the MN and BN groups

At time of biopsy

 Sex (male:female)

160:34

81:26

79:8

0.006

 Age (y)

43.8 ± 4.1

47.4 ± 10.3

39.4 ± 10.7

<0.001

 Hypertension family history

114(58.8 %)

59(55.1 %)

55(63.2 %)

0.26

 Hypertension duration (y)

5.0(1.0-9.0)

6.0(2.4-10.0)

3.0(0.2-7.0)

<0.001

 SBP (mmHg)

195 ± 37

182 ± 32

213 ± 32

<0.001

 DBP (mmHg)

126 ± 26

119 ± 23

138 ± 25

<0.001

 MAP (mmHg)

150 ± 27

139 ± 24

163 ± 25

<0.001

 Current smoker

57(29.4 %)

30(28.0 %)

27(31.0 %)

0.65

 Grades of retinopathy

  I-II (%) (n*)

73(50.3 %)(145)

44(58.7 %)(75)

29(41.4 %)(70)

<0.001

  III-IV (%) (n*)

42(29.0 %)(145)

8(10.7 %)(75)

34(48.6 %)(70)

 Hypertensive heart disease

110(56.7 %)

42(39.3 %)

68(78.2 %)

<0.001

 Hypertensive cerebrovascular disease

18(9.3 %)

12(11.2 %)

6(6.9 %)

0.30

 Scr (mg/dl)

1.61(1.24-2.27)

1.35(1.07-1.60)

2.27(1.74-3.14)

<0.001

 eGFR (ml/min/1.73 m²)

49.6(32.8-65.7)

60.5(48.9-76.5)

34.5(24.2-46.8)

<0.001

 eGFR < 60 ml/min/1.73 m²

130(67.0 %)

51(47.7 %)

79(90.8 %)

<0.001

 Uric acid (μmol/l)

455 ± 109

437 ± 111

482 ± 101

0.004

 Anemia

36(18.6 %)

10(9.3 %)

26(29.9 %)

<0.001

 Elevated LDH

5(2.6 %)

0(0 %)

5(5.7 %)

-

 Thrombocytopenia

1(0.5 %)

0(0 %)

1(1.1 %)

-

 Proteinuria (g/24 h)

0.80(0.42-1.48)

0.72(0.38-1.34)

0.89(0.58-1.57)

0.02

 Microscopic hematuria

46(23.7 %)

31(29.0 %)

15(17.2 %)

0.06

Follow-up

 No. of antihypertensive drugs

2.7 ± 1.3

2.3 ± 1.1

3.3 ± 1.2

<0.001

 Time-average MAP (mmHg) (n*)

129 ± 13(157)

124 ± 11(88)

135 ± 14(69)

<0.001

 ESRD

36(18.6 %)

7(6.5 %)

29(33.3 %)

<0.001