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Table 3 Associations with remission: Individual-level meta-regression of available data

From: The role of plasma exchange in treating post-transplant focal segmental glomerulosclerosis: A systematic review and meta-analysis of 77 case-reports and case-series

 

OR (95 % CI)

Adults vs. children (235 patients; 55 studies)

1.09 (0.55 to 2.16)

Males vs. females (212 patients; 54 studies)

2.85 (1.44 to 5.62)

Proteinuria at recurrence (≥7 g/day vs. <7 g/day) (148 patients; 40 studies)

0.43 (0.19 to 0.97)

Received rituximab (404 patients; 72 studies)

0.60 (0.21 to 1.75)

Transplant type (living vs. deceased) (423 patients; 46 studies)

1.00 (0.43 to 2.30)

Plasma exchange within 2 weeks of FSGS recurrence (230 patients; 54 studies)

2.16 (0.93 to 5.01)

  1. Odds ratios (OR) and 95 % confidence intervals estimated using generalized linear estimating equations to account for within-study clustering