Table 2 Standardised¹ incidence rates for ESKD, dialysis, CVD and mortality

	All participants			ACR <3.5 mg/mmol ^d			ACR ≥3.5 mg/mmol ^d
Outcome	Events	Person-years^b	Incidence^c (95%CI)	Events	Person-years^b	Incidence^c (95%CI)	Events	Person-years^b	Incidence (95%CI)
Diagnosis
ESKD	16	5,961	340 (334–346)	2	4,001	70 (67–73)	12	1,691	789 (774–809)
Dialysis	13	5,976	212 (202–222)	1	4,000	26 (22–31)	10	1,706	512 (484–539)
CVD	67	5,769	1,060 (1037–1083)	33	3,909	868 (841–895)	31	1,604	1437 (1391–1483)
Mortality
Renal death	4	6,009	61 (60–62)	0	4,001	-	3	1,734	125 (122–128)
All chronic disease deaths combined^e	19	6,009	283 (276–290)	8	4,001	203 (196–211)	9	1,734	364 (351–377)
Non-traumatic death^f	40	6,009	617 (603–631)	17	4,002	446 (430–461)	17	1,734	746 (721–772)
All-cause mortality	53	6,009	860 (839–880)	28	4,002	730 (707–754)	18	1,734	904 (867–941)

^aThe standard population used is the non-diabetic cohort members; ^bperson-years = time from recruitment until incident diagnosis or end of follow up period and rounded to nearest full number; ^cper 100,000 person-years, showing age and gender adjusted standardised incidence rate; ^dexcludes 30 participants without a baseline ACR measurement; ^eCVD, renal, cancer or diabetic cause of death; ^fexcluding a traumatic cause of death. NB: A total of 53 participants died during the follow-up period (all-cause mortality), of which 40 were considered non-traumatic deaths (that is, not including deaths such as motor vehicle accidents and homicides). Of the non-traumatic deaths, any underlying cause of death attributed to a chronic disease, including CVD, renal disease, cancer or diabetes was considered a chronic disease death (n = 19). Of the chronic disease attributed deaths, four had renal underlying causes recorded. The difference between the numbers of all participants and the ACR categories is due to the 30 participants without a baseline ACR measurement. ESKD End stage kidney disease, CVD Cardiovascular disease, ACR Albumin creatinine ratio

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