Fig. 1

No difference in the progression of kidney atrophy between CLU KO mice and WT controls after IRI. Renal IRI in left kidneys of CLU KO versus WT mice was induced by clamping renal pedicles for 28 min at the body temperature of 32 °C, and the weight of the left kidney and contralateral right kidney from each mouse was recorded at different time points after reperfusion. Data are presented in the figure as mean ± standard error of the mean (SEM) of each group. KO-IRI: the left kidneys of CLU KO mice (n = 4–15) after IRI (p = 0.0073, one-way ANOVA); KO-Contralateral: the right/contralateral kidneys of CLU KO mice (p = 0.0553, one-way ANOVA); WT-IRI: the left kidneys of WT mice (n = 4–22) after IRI (p = 0.0060, one-way ANOVA); and WT-Contralateral: the right/contralateral kidneys of CLU KO mice (p = 0.5140, one-way ANOVA). Kidney atrophy in KO versus WT mice, p = 0.3542 (two-way ANOVA)