Fig. 3
No difference in tissue architecture of the kidneys between CLU KO and WT mice on day 14 after IRI. The sections of the left kidneys of WT versus CLU KO mice, harvested on day 14 after reperfusion, were stained with hematoxylin and eosin (HE) or Masson’s trichrome (MT). Data are presented as a typical microscopic image of renal cortex. KO: CLU null kidney sections; WT: WT kidney sections. a Typical microscopic images of HE-stained sections showing intact tubules with minimal cellular infiltration in the perivascular space. b Typical microscopic images of MT-stained sections showing red cytoplasm and mild blue collagen in the perivascular space. Black arrows: glomeruli; IA: interlobular artery; and IV: interlobular vein. c The infiltration was semi-quantitatively scored in two separate sections of each injured left kidney, and was presented in average per view. Data are presented as mean ± SD of each group. KO group vs. WT control: P = 0.1510 (two-tailed t-test, n = 9). d The interstitial fibrosis was semi-quantitatively scored in two separate sections of each injured left kidney, and was presented in average per view. Data are presented as mean ± SD of each group. KO group vs. WT control: P = 0.1284 (two-tailed t-test, n = 9)