Fig. 2

G-CSF treatment ameliorated histologic injury and immune deposits in lupus nephritis. a Representative kidney sections stained with PAS (200×; histological score on the right-panel). b Frozen sections stained for IgG and C3 deposits (200×; immunofluorescence staining score on the right-panel). Scores of both histologic injury and immune deposits were lower in the G-CSF group than the PBS group. Differences in histologic injury and immune deposit scores were analyzed by t tests. The data are expressed as the mean ± standard error of the mean, with n = 14 − 16 mice per group. White and black bars indicate the G-CSF group and the PBS group, respectively. *P < 0.05, **P < 0.01 for comparisons between the G-CSF and the PBS groups. C3: complement component 3; G-CSF, granulocyte colony-stimulating factor: PAS, periodic acid-Schiff’s reagent; PBS: phosphate-buffered saline