Table 1 Clinical data at the time of renal biopsy of lupus nephritis patients classified according to the ISN/RPS 2003. Data expressed as mean ± SD unless otherwise specified
From: Relation of peritubular capillary features to class of lupus nephritis
Lupus nephritis classes (N = 253) | Class II (N = 23) | Class III (N = 6) | Class IV (N = 171) | Class IV + V (N = 3) | Class V (N = 50) |
|---|---|---|---|---|---|
Age at biopsy (years) | 34 ± 10 | 39 ± 14 | 33 ± 12 | 35 ± 10 | 36 ± 12 |
Male : Female (n) | 3:20 | 2:4 | 27:144 | 0:3 | 9:41 |
SBP (mmHg) | 129 ± 15 | 134 ± 22 | 140 ± 24b | 125 ± 19 | 125 ± 16h |
DBP (mmHg) | 80 ± 9 | 86 ± 17 | 86 ± 16b | 82 ± 16 | 80 ± 14 |
Blood urea nitrogen (mg/dL) | 13.9 ± 6.9 | 33.0 ± 21.3a | 41.9 ± 32.4b | 21.4 ± 3.2c,g | 19.4 ± 13.8d,f,h |
Serum creatinine (mg/dL) | 0.75 ± 0.21 | 1.60 ± 1.17a | 1.92 ± 1.49b | 0.83 ± 0.15g | 0.80 ± 0.33f,h |
eGFR (mL/min/1.73 m2) | 109 ± 22 | 71 ± 44a | 59 ± 38b | 95 ± 25 | 102 ± 30f,h |
Serum albumin (g/dL) | 3.27 ± 0.54 | 3.20 ± 0.23 | 2.65 ± 0.81b,e | 2.87 ± 0.81 | 2.81 ± 0.88 |
Serum complement (mg/dL) | |||||
 C3 concentration | 102 ± 47 | 108 ± 45 | 67 ± 102b | 57 ± 28 | 97 ± 45h |
 C4 concentration | 25 ± 18 | 26 ± 15 | 16 ± 18 | 8 ± 4c,g | 22 ± 13h,i |
Urinary protein (g/24 h) | 2.60 ± 1.51 | 1.85 ± 0.70 | 3.69 ± 2.85b,e | 3.23 ± 1.70 | 3.53 ± 2.05d,f |
Urinary RBC (cells/HPF) | 19 ± 39 | 45 ± 62 | 26 ± 35 | 4 ± 3g | 4 ± 7d,f,h |
Urinary WBC (cells/HPF) | 10 ± 26 | 17 ± 30 | 13 ± 24 | 5 ± 8 | 3 ± 5f,h |
Tubular atrophy scores (% of patients)&& 0/1/2 | 67/27/6 | 33/67/0 | 25/40/35 | 33/33/33 | 47/38/15 |
Interstitial inflammatory cells infiltration scores (% of patients)&& 0/1/2/3 | 71/29/0/0 | 33/33/17/17 | 28/58/12/2 | 33/33/33/0 | 77/23/0/0 |
Interstitial fibrosis scores (% of patients)&& 0/1/2/3 | 67/27/13/0 | 33/67/0/0 | 28/66/4/2 | 33/33/33/0 | 55/32/13/0 |