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Table 2 Multivariate analysis of the clinical factors associated with percent of PTC change

From: Relation of peritubular capillary features to class of lupus nephritis

Clinical factors

%PTC (Mean ± SD)

Unadjusted mean difference (95 % Confidence interval)

Adjusted mean difference (95 % Confidence interval)

p-value

LN classes

 II

1.95 ± 1.50

Reference

Reference

 

 III

4.16 ± 3.85

2.21 (−1.54 to 5.96)

2.67 (−1.79 to 7.13)

0.239

 IVa

4.20 ± 4.41

2.25 (0.11 to 4.39)

2.43 (0.02 to 4.84)

0.042**

 V

4.45 ± 3.75

2.59 (0.11 to 4.88)

2.46 (0.02 to 5.00)

0.047**

Hematuria (cells/HPF)

 <3

3.55 ± 3.35

Reference

Reference

 

 3–10

5.78 ± 5.17

2.22 (0.69 to 3.75)

1.96 (0.25 to 3.67)

0.025**

 10–30

4.69 ± 4.65

1.13 (−0.50 to 2.77)

0.92 (−1.03 to 2.88)

0.353

 >30

3.21 ± 3.91

−0.35 (−1.84 to 1.15)

−0.11 (−1.92 to 1.70)

0.904

eGFR (mL/min/1.73 m2)

 ≥60

4.42 ± 4.12

Reference

Reference

 

 15–59

3.29 ± 3.40

−1.13 (−2.26 to −0.01)

−1.32 (−2.62 to-0.02)

0.046**

 <15

5.09 ± 4.72

0.66 (−1.67 to 3.00)

−0.18 (−2.70 to 2.34)

0.117

Urinary protein (mg/day)

 <500

4.90 ± 4.46

Reference

Reference

 

 500–999

2.31 ± 1.69

−2.59 (−5.26 to 0.07)

−2.45 (−5.17 to 0.27)

0.077

 1,000–1,999

4.35 ± 4.09

−0.55 (−2.90 to 1.80)

−1.04 (−3.47 to 1.39)

0.399

 2,000–2,999

3.89 ± 3.86

−1.02 (−3.33 to 1.30)

−1.36 (−3.79 to 1.07)

0.269

 ≥3,000

3.14 ± 2.64

−1.77 (−3.96 to 0.43)

−2.08 (−4.31 to 0.15)

0.067

  1. Notes: %PTC; percentage of peritubular capillary, eGFR; estimated glomerular filtration rate, calculated according to CKD-EPI formula
  2. aincluded LN class IV + V, **statistical significant p < 0.05