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Table 3 Correlation coefficients between the changes of plasma sclerostin concentration and changes of serum calcium, phosphate and PTH concentration, as well as the dose of cinacalcet after 3 and 6 months of treatment

From: Treatment with cinacalcet increases plasma sclerostin concentration in hemodialysis patients with secondary hyperparathyroidism

 

Change of plasma sclerostin [ng/ml]

0–3 months

0–6 months

change of serum calcium [mmol/l]

0–3 months

R = -0.31; p = 0.03

 

0–6 months

 

R = -0.37; p = 0.009

change of serum phosphate [mmol/l]

0–3 months

R = 0.01; p = 0.96

 

0–6 months

 

R = -0.06; p = 0.67

change of serum PTH [pg/ml]

0–3 months

R = -0.07; p = 0.64

 

0–6 months

 

R = -0.18; p = 0.21

cinacalcet dose [mg]

0–3 months

R = -0.13; p = 0.36

 

0–6 months

 

R = -0.15; p = 0.29

  1. PTH parathyroid hormone