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Table 3 Associations of physical activity with metabolic health outcomes in SUGAR

From: Physical activity and metabolic health in chronic kidney disease: a cross-sectional study

 

Unadjusted

Model 1

Model 2

Model 3

Outcomes:

 Insulin sensitivity (mg/min)/(μU/mL)

1.0 (0.4, 1.5)

0.8 (0.2, 1.4)

0.9 (0.2, 1.5)

0.7 (0.0, 1.4)

  P Value

0.0003

0.009

0.006

0.04

 Fat mass (kg)

−6.3 (−10.3, −2.2)

−8.2 (−12.8, −3.6)

−8.0 (−12.9, −3.1)

NA

  P Value

0.002

0.0005

0.001

NA

 BMI (kg/m2)

−2.7 (−4.6, −0.8)

−3.6 (−5.8, −1.5)

−3.6 (−5.9, −1.3)

NA

  P Value

0.005

0.0007

0.002

NA

 CRP (% difference)

−33 (−51, −7)

−32 (−50, −6)

−24 (−48, 13)

−5 (−37, 43)

  P Value

0.01

0.02

0.17

0.83

 HDL (mg/dL)

5.6 (−2.3, 13.5)

6.6 (−2.0, 15.3)

6.8 (−0.8, 14.4)

5.5 (−1.5, 12.5)

  P Value

0.17

0.13

0.08

0.12

 Triglycerides (mg/dL)

−39.9 (−72.4, −7.5)

−45.0 (−76.2, −13.9)

−37.9 (−71.9, −3.9)

−22.7 (−57.0, 11.6)

  P Value

0.02

0.005

0.03

0.20

 Systolic BP (mm Hg)

−5.8 (−10.7, −1.0)

−4.5 (−9.1, 0.0)

−3.0 (−8.0, 2.0)

0.2 (−4.6, 5.1)

  P Value

0.02

0.053

0.24

0.93

 Diastolic BP (mm Hg)

0.3 (−2.9, 3.5)

−1.2 (−4.1, 1.7)

−1.1 (−4.2, 1.9)

−0.5 (−3.5, 2.6)

  P Value

0.87

0.42

0.47

0.77

  1. Entries are the difference (95% CI) in the outcome associated with a doubling in accelerometry mean counts per minute. Model 1 adjusts for age, sex, and race (white/black/other). Model 2 additionally adjusts for cardiovascular disease and eGFR. For HDL and triglycerides outcomes, Model 2 additionally adjusts for statins, fibrates, and niacin medications; for BP outcomes, Model 2 additionally adjusts for the number of hypertension medications. Model 3 adjusts for Model 2 variables plus fat mass. BMI body mass index, CRP C-reactive protein, HDL high density lipoprotein cholesterol, BP blood pressure