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Table 4 Associations of physical activity with metabolic health outcomes in SUGAR, by CKD status

From: Physical activity and metabolic health in chronic kidney disease: a cross-sectional study

Dependent variable

CKD

Non CKD

 
 

Mean (SD)b

Adjusted difference (95% CI)a

Mean (SD)b

Adjusted difference (95% CI)a

P value for Interaction

Insulin sensitivity (mg/min)/(μU/mL)

4.1 (2.1)

0.8 (0.2, 1.4)

5.2 (2.0)

1.0 (0.1, 1.9)

0.73

Fat mass (kg)

32.0 (11.4)

−4.9 (−10.2, 0.4)

29.4 (14.8)

−13.2 (−20.2, −6.2)

0.045

BMI (kg/m2)

30.0 (5.5)

−2.0 (−4.5, 0.6)

28.0 (6.8)

−6.3 (−9.4, −3.2)

0.03

CRP (percent difference)

0.3 (2.6)

−11 (−44, 43)

0.1 (2.8)

−41 (−66, 2)

0.26

HDL (mg/dL)

52.4 (22.4)

2.2 (−8.2, 12.6)

58.7 (18.9)

13.9 (5.8, 22.0)

0.07

Triglycerides (mg/dL)

153.2 (91.6)

−39.8 (−90.3, 10.8)

99.6 (66.8)

−30.7 (−57.9, −3.5)

0.76

Systolic BP (mmHg)

134.5 (14.3)

−0.2 (−6.3, 6.0)

122.6 (13.9)

−7.5 (−13.1, −2.0)

0.07

Diastolic BP (mmHg)

79.6 (9.5)

1.3 (−2.4, 5.1)

76.4 (10.1)

−5.2 (−8.5, −1.9)

0.007

  1. aDifference per doubling of CPM, adjusted for age, sex, race (white/black/other), cardiovascular disease, eGFR. Lipid-lowering medications (statins, fibrates, and niacin medications, included for HDL-cholesterol and triglycerides only), and antihypertensive medications (yes/no and number of antihypertensive medications, for systolic and diastolic BP only), as in Model 2 of Table 3
  2. bEntry for CRP is geometric mean (SD)