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Table 2 Characteristics of users and non-users of non-steroidal anti-inflammatory drugs (NSAIDs) among 826 acute kidney injury (AKI) survivors in the Southern Community Cohort Study

From: High prevalence of non-steroidal anti-inflammatory drug use among acute kidney injury survivors in the southern community cohort study

Characteristic

NSAID usersa,c

N = 154

NSAID non-usersa,c

N = 438

Unknown NSAIDa,c

N = 234

Totala,c

N = 826

Median difference between NSAID users and non-usersd

Age at enrollment, years

57.5 (50.0, 66.0)

58.0 (50.0, 66.0)

57.0 (50.0, 65.0)

57.0 (50.0, 66.0)

−0.5 (−4.1, 1.6)

Recruitment source

 CHC

111 (72)

406 (93)

218 (93)

735 (89)

 

 General population

43 (28)

32 (7)

16 (7)

91 (11)

 

Race

 Black

79 (53)

280 (64)

176 (77)

535 (66)

 

 White

66 (44)

137 (31)

42 (18)

245 (30)

 

 Other

4 (3)

20 (5)

12 (5)

36 (4)

 

Male

66 (43)

215 (49)

108 (46)

389 (47)

−6.2 (−15.8, 3.3)

Income < $15,000

113 (75)

336 (76)

190 (80)

629 (77)

1.1 (−7.3, 9.5)

Education

 < High school

46 (31)

177 (41)

105 (47)

328 (41)

 

 High school

46 (31)

141 (32)

70 (32)

257 (32)

 

 > High school

57 (38)

118 (27)

47 (21)

222 (28)

 

Insurance coverage

143 (93)

398 (91)

204 (93)

204 (93)

2.4 (−2.8, 7.6)

Most recent doctor visit, months

 0

53 (36)

185 (43)

86 (40)

324 (41)

 

 1

56 (38)

133 (31)

79 (37)

268 (34)

 

 2

20 (14)

33 (8)

24 (11)

77 (10)

 

 3

19 (13)

76 (18)

26 (12)

121 (15)

 

BMI, kg/m2

30.0 (26.1, 36.7)

29.4 (25.6, 36.0)

29.2 (24.2, 35.9)

29.4 (25.3, 36.1)

0.7 (−0.5, 1.9)

Regular use of:

 Low-dose aspirin

66 (44)

162 (37)

59 (27)

287 (36)

 

 Regular aspirin

34 (24)

64 (15)

41 (19)

139 (18)

 

 Acetaminophen

50 (35)

62 (14)

18 (9)

130 (17)

 

NSAID sourceb

 Prescription

52 (34)

-

-

52 (34)

 

 OTC

81 (53)

-

-

81 (53)

 

 Both

21 (14)

-

-

21 (14)

 

Diabetes

54 (35)

233 (53)

114 (51)

401 (49)

−18.1 (−27.4, −8.8)

Hypertension

128 (83)

348 (79)

181 (81)

657 (81)

3.7 (−3.8, 11.1)

Myocardial infarction

29 (19)

117 (27)

52 (23)

198 (24)

−7.8 (−15.7, 0.2)

Arthritis

109 (71)

187 (43)

108 (48)

404 (50)

28.1 (19.1, 37.1)

Ulcer

41 (27)

77 (18)

38 (17)

156 (19)

9.0 (0.7, 17.3)

Lupus

4 (3)

6 (1)

4 (2)

14 (2)

1.2 (−2.0, 4.4)

High cholesterol

78 (51)

223 (51)

104 (47)

405 (50)

−0.1 (−9.3, 9.2)

Heart failure

68 (44)

224 (51)

119 (51)

411 (50)

−7.0 (−16.6, 2.6)

Chronic kidney disease

55 (36)

215 (49)

91 (39)

361 (44)

−13.4 (−22.7, −4.0)

  1. aData presented as median (25th, 75th percentile) for continuous variables and N (%) for categorical variables
  2. bPercentages sum to >100% due to rounding
  3. cn may not sum to 826 due to missing data
  4. dPresented as median difference for continuous variables and proportion difference for categorical variables