Table 5 Summary of the studies in urine and plasma biomarkers for sepsis-related acute kidney injury

Martensson et al. (2010) [12]

NGAL^a (ng/mg creatinine)

0.86

0.68-1.0

12 h following septic shock

>68

0.71

1.0

Su et al. (2011) [40]

sTREM-1^a (pg/mL)

0.92

0.85-0.99

48 h before AKI diagnosis^c

69.04

0.94

0.76

Aydogdu et al. (2013) [41]

Cys-C^a (mg/L)

0.86

-

Within 8 days after

admission

0.106

0.85

0.80

NGAL^a (ng/mL)

0.80

-

29.5

0.88

0.73

Fan et al. (2014) [30]

NGAL^a (ng/mL)

0.86

0.81-0.93

7 days after onset of sepsis

402

0.89

0.74

Matsa et al. (2014) [42]

NGAL^a (ng/mL)

0.78

-

24 h after admission

350

0.75

0.82

Terzi et al. (2014) [43]

α1m^a (mg/L)

0.74

-

24 h before AKI onset

47.9

0.88

0.62

Dai et al. (2015) [44]

Cys-C^a (mg/L)

0.74

0.64-0.84

24 h before AKI onset

N/A

N/A

N/A

NGAL^a (ng/mL)

0.88

0.79-0.95

N/A

N/A

N/A

sTREM-1^a (pg/mL)

0.78

0.69-0.87

N/A

N/A

N/A

The present study

ATF3^b (ng/mL)

0.84

0.77-0.91

24 h before AKI onset

12

0.93

0.85

NGAL^b (ng/mL)

0.64

0.54-0.74

150

0.98

0.44

Martensson et al. (2010) [12]

NGAL (ng/mL)

0.67

0.39-0.94

12 h following septic shock

>120

0.83

0.50

Aydogdu et al. (2013) [41]

Cys-C (mg/L)

0.82

-

Within 8 days of admission

1.5

0.73

0.68

NGAL (ng/mL)

0.44

-

N/A

N/A

N/A

Matsa et al. (2014) [42]

NGAL (ng/mL)

0.88

-

24 h after admission

400

0.79

0.75

Nakamura et al. (2014) [45]

Presepsin (pg/mL)

0.70

-

Within 24 h of admission

670

0.70

0.81

Nakamura et al. (2015) [46]

Procalcitonin (ng/mL)

0.88

-

Within 24 h of admission

0.42

0.95

0.65

Dai et al. (2015) [44]

Cys-C (mg/L)

0.74

0.63-0.84

24 h before AKI onset

N/A

N/A

N/A

NGAL (ng/mL)

0.83

0.74-0.92

N/A

N/A

N/A

sTREM-1 (pg/mL)

0.75

0.65-0.85

N/A

N/A

N/A