Offering Patients Therapy Options in Unplanned Start (OPTiONS): Implementation of an educational program is feasible and effective

Table 1 Baseline characteristics of all 270 UPS patients, 214 patients who received UPS-EP and 56 patients who did not receive UPS-EP

	UPS patients n = 270	Received UPS-EP n = 214	Not received UPS-EP n = 56	P value
Age	69 (40-83)	67 (37-84)	72 (54 – 83)	0.01
Sex, M/F, %	64/36	64/36	64/36	1.00
eGFR, ml/min /1.73 m² BSA	7 [4–16]	7 [4–16]	7 [4–16]	0.53
Charlson comorbidity index, CCI	6 [2–10]	6 [2–10]	7 [5–10]	<0.01
Comorbidities, %
Diabetes Congestive heart failure Myocardial infarct Peripheral vascular disease	41 31 18 18	39 28 17 16	50 41 21 25	0.17 0.07 0.56 0.12
Primary renal disease^a, %
Chronic renal failure, etiology unknown Glomerulonephritis Renal vascular disease Diabetic nephropathy Other ^b	13 20 20 25 22	12 22 18 23 25	14 14 16 32 24	0.59
Patients source, %
In-patient admission Out-patient referral	71 29	68 32	80 20	0.09
Referral, %
Primary care Other hospital specialty Missing/unknown	51 48 1	53 46 1	48 52 0	0.64
Hospitalization for the unplanned start, %	91	90	93	0.80
Countries, %
United Kingdom Germany Denmark Sweden Austria France	24 36 18 4 11 7	29 34 17 5 7 8	5 43 20 2 28 2	<0.001

Values are expressed as median (10-90 percentiles) or percentage. CCI, Charlson comorbidity index; eGFR, estimated glomerular filtration rate, significant values are marked in bold (p < 0.05)
^aCause of renal disease
^bPyelonephritis, interstitial nephropathy, cystic kidney disease, inherited renal disease, renal hypoplasia, multisystem renal disease, myeloma, amyloid, other renal disease

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