Table 2 Conclusions of the study performed by Nasim et al

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DHF / DSS commoner in subjects on high dose steroids

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Secondary infection on cyclosporine, a significantly lesser proportion of patients presented, with less severe disease DHF/DSS vs DF (p = 0.04)

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Fever is commoner in patients taking low dose steroids to patients on high-dose steroids (p = 0.013)

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The anti-mitotic agents (azathioprine (AZA) or mychophenolate mofetil (MMF)) have no effect; on the severity or duration of thrombocytopenia;leucopenia; and occurrence of gastro-intestinal symptoms.

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Mean duration of thrombocytopenia is longer in patients on regimens containing tacrolimus

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Patients on tacrolimus containing regimens have a higher mortality (p = 0.02)

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Percentage rise in creatinine from pre-dengue levels was higher in DHF/DSS patients than in DF patients (p < 0.001)

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Majority (85.7%) who had graft dysfunction, creatinine returned to base line by 12.6 days, whereas in 14.3% it persisted beyond 6 weeks.

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All the patients who died had graft dysfunction

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Of 21 patients who were IgM positive and IgG negative in the initial sample, 10 (48%) had not mounted an IgG response by an average of 15 weeks

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No statistically significant difference was found in the number of years as transplantation of those who survived vs. those who died