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Table 2 Predictive factors for ESRD by univariate and multivariate logistic regression

From: Risk factors of progressive IgA nephropathy which progress to end stage renal disease within ten years: a case–control study

 

Univariate Logistic

Multivariate Logistic

OR (95%CI)

P

OR (95%CI)

P

Mesangial hypercellularity

 M0

1

 

1

 

 M1

9.12 (4.10–20.27)

<0.001

5.10 (1.33–19.60)

0.018

Endocapillary hypercellularity

 E0

1

 

1

 

 E1

1.21 (0.57–2.55)

0.617

1.62 (0.33–8.02)

0.557

Segmental Glomerulosclerosis

 S0

1

 

1

 

 S1

3.43 (1.61–7.32)

0.001

0.57 (0.12–2.74)

0.480

Tubular atrophy/interstitial fibrosis

 T0

1

 

1

 

 T1

12.71 (5.25–30.76)

<0.001

1.82 (0.33–10.0)

0.492

 T2

14.33 (3.43–59.91)

<0.001

0.32 (0.02–5.48)

0.431

At the time of biopsy

 eGFR

0.96 (0.94–0.97)

<0.001

0.97 (0.93–0.998)

0.039

 Gender (male)

1.83 (0.89–3.78)

0.100

5.38 (0.82–35.49)

0.081

 Age

1.0 (0.97–1.04)

0.830

0.92 (0.83–1.01)

0.087

 UA

1.74 (1.39–2.16)

<0.001

0.94 (0.59–1.50)

0.795

 Hb

0.82 (0.68–0.99)

0.039

1.14 (0.60–2.17)

0.692

 Alb

0.40 (0.24–0.67)

0.001

0.53 (0.18–1.62)

0.267

 TC

1.01 (1.0–1.02)

0.006

1.003 (0.99–1.02)

0.687

 24 h urine protein

1.60 (1.30–1.96)

<0.001

1.17 (0.86–1.58)

0.313

 Hypertension (yes)

1.84 (0.92–3.68)

0.085

4.33 (0.79–23.80)

0.092

 Macro-hematuria (yes)

0.19 (0.04–0.85)

0.030

0.05 (0–9.02)

0.264

Follow-up

 TA-UA

2.36 (1.74–3.19)

<0.001

2.06 (1.09–3.90)

0.026

 TA-Hb

0.61 (0.48–0.76)

<0.001

0.53 (0.30–0.91)

0.029

 TA-Alb

0.18 (0.08–0.38)

<0.001

0.48 (0.10–2.37)

0.367

 TA-TC

1.01 (1.0–1.02)

0.002

1.004 (0.99–1.02)

0.697

  1. OR odds ratio, 95% CI 95% confidence interval