BMC Nephrology

Table 4 Crude and adjusted^a all-cause and CVD-related mortality grouped according to BMI and ghrelin levels^b

From: Interaction between acyl-ghrelin and BMI predicts clinical outcomes in hemodialysis patients

Variable		All-cause mortality		Cardiovascular mortality
Variable		HR (95% CI)	P	HR (95% CI)	P
Low BMI, low AG (n = 51)	Crude	1.0		1.0
Low BMI, low AG (n = 51)	Adjusted	1.0^c		1.0^c
Low BMI, high AG (n = 80)	Crude	0.72 (0.44–1.19)	0.20	0.58 (0.29–1.19)	0.14
Low BMI, high AG (n = 80)	Adjusted	0.71 (0.42–1.23)	0.23	0.64 (0.29–1.39)	0.26
High BMI, low AG (n = 78)	Crude	0.64 (0.38–1.08)	0.10	0.52 (0.29–1.10)	0.09
High BMI, low AG (n = 78)	Adjusted	0.63 (0.35–1.11)	0.11	0.51 (0.22–1.15)	0.10
High BMI, high AG (n = 52)	Crude	0.36 (0.19–0.68)	0.002	0.33 (0.13–0.82)	0.02
High BMI, high AG (n = 52)	Adjusted	0.31 (0.16–0.62)	0.001	0.35 (0.13–0.91)	0.03

Abbreviations: CI Confidence interval, HR Hazard ratio, CVD Cardiovascular disease in the past, BMI Body mass index, AG Acyl-ghrelin
^aAdjusted for age, gender, DM status, dialysis vintage, co-morbidity index, smoking, Kt/V, cholesterol and IL-6
^bThe low BMI or AG group was defined as BMI <26. 8 kg/m2 or Gh < 128.5 pg/ml - values below the medians of distribution
^cThe group of patients who had low BMI (defined as BMI levels below median) and low acyl-ghrelin (defined as acyl-ghrelin levels below median) was used as a reference

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ISSN: 1471-2369

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