Fig. 1
From: Protective effect of quinacrine against glycerol-induced acute kidney injury in rats
Blood urea nitrogen and serum creatinine levels. a. The effect of quinacrine on glycerol induced changes in BUN. Glycerol produced a significant (P < 0.001) increase in BUN as compare to control group (###). Treatment of rats with quinacrine in the doses of 3 mg/kg (P < 0.05), 10 mg/kg (P < 0.05) and 30 mg/kg (P < 0.01) significantly attenuated glycerol induced rise in BUN (* values compared to glycerol treated group). b. The effect of quinacrine on glycerol induced changes in Scr. Glycerol produced a significant (P < 0.01) increase in Scr. as compare to control group (##). Treatment of rats with quinacrine in the doses of 3 mg/kg (P < 0.05), 10 mg/kg (P < 0.05) and 30 mg/kg (P < 0.01) significantly attenuated glycerol induced rise in Scr. (* values compared to glycerol treated group)