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Table 4 Effect of Quinacrine on glycerol induced histopathological changes in kidney (higher scores indicate severe injury)

From: Protective effect of quinacrine against glycerol-induced acute kidney injury in rats

Groups Tubular dilatation Tubular voculation Tubular necrosis
Control 0 0 0
Glycerol25% 3.37 ± 0.18### 1.43 ± 0.290# 0.875 ± 0.182##
QRN 3 mg/kg + GLY 2.50 ± 0.25* 1.25 ± 0.163 0.812 ± 0.209
QRN 10 mg/kg + GLY 1.87 ± 0.27** 0.81 ± 0.209 0.375 ± 0.125*
QRN 30 mg/kg + GLY 1.37 ± 1** 0.62 ± 0.081* 0.125 ± 0.125**
  1. Effect of quinacrine on glycerol-induced AKI.. Glycerol treated rats developed significant histological changes in kidney tubules. Data expressed in mean ± SE. # P < 0.05, ## P < 0.01 and ### P < 0.001 as compare to control group; *P < 0.05, and ** P < 0.001 as compare to glycerol treated group (G.3)