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Table 2 Peritonitis outcomes at 18 months

From: Peritonitis outcomes in patients with HIV and end-stage renal failure on peritoneal dialysis: a prospective cohort study

 

HIV-Negative

HIV-Positive

P value

Peritonitis episodes, n (n excluding relapse)a

54 (49)

94 (81)

0.001b

Participants with a peritonitis episode at 180 dayse

24.3% (17/70)

51.4% (36/70)

0.001

Participants with a peritonitis episode at 1 yeare

38.6% (27/70)

60.0% (42/70)

0.011

Participants with a peritonitis episode at 18 monthse

44.3% (31/70)

65.7% (46/70)

0.011

Multiple peritonitis episodes

 Time between peritonitis episodes (days), median (IQR)

75 (39–107)

55.5 (34.5–115.5)

0.503d

   Relapse

9.2% (5/54)

13.8% (13/94)

0.602c

   Recurrent

3.7% (2/54)

6.4% (6/94)

0.711c

   Repeat (Same organism)

11.1% (6/54)

7.4% (7/94)

0.448b

   Repeat (Different organism)

18.5% (10/54)

23.4% (22/94)

0.487b

Time - Tenckhoff catheter insertion to peritonitis episode

 Median, days (IQR)

184.5 (98–370)

144.5 (63–296)

0.124d

 Within 180 days

50.0% (27/54)

56.4% (53/94)

0.453b

 Between 180 – 365 days

24.1% (13/54)

27.7% (26/94)

0.634b

 Between 365 – 550 days

25.9% (14/54)

16.0% (15/94)

0.141b

PD WCC (cells/μl), median (IQR)

1073 (360–2690)

979 (360–2370)

0.927d

Outpatient treatment

33.3% (18/54)

40.4% (38/94)

0.392b

Inpatient treatment

66.7% (36/54)

59.6% (56/94)

0.392b

Inpatient stay (days), median (IQR)

9 (7–12)

8 (7–14.5)

0.574d

Peritonitis episode outcomes

 CAPD continuation

70.4% (38/54)

78.7% (74/94)

0.254b

 Catheter removal

25.9% (14/54)

17.0% (16/94)

0.195b

 Mortality

3.7% (2/54)

4.3% (4/94)

1.000c

  1. IQR interquartile range, PD peritoneal dialysis, WCC white blood cell count, CAPD continuous ambulatory peritoneal dialysis, HIV human immunodeficiency virus
  2. aPeritonitis episode count excluding peritonitis relapse, bPearson’s χ 2 test, cFisher’s exact test
  3. dWilcoxon rank-sum (Mann-Whitney) test, ePeritonitis experience – documented 1 or more of peritonitis episodes