Fig. 1
From: A rare case of renal thrombotic microangiopathy associated with Castleman’s disease
Histopathological findings in renal and the inguinal lymph node biopsies from the patient with MCD. Renal (a-d) and lymph node biopsies (e-f) at the onset of disease. a Diffuse endocapillary proliferation and endothelial swelling (Hematoxylin and eosin stain [H&E], ×400). b Thrombi within capillary loops (arrow; Masson trichrome, ×200). c Mesangiolysis (arrow) and double contour (Jones Methenamine Silver, ×200). d Transmission electron microscopy showed diffuse endothelial swelling with obliteration of capillary lumina and mesangial interposition (×4000). e Hyalinization of the germinal center and concentric layering of peripheral lymphocytes (H&E, ×200). f Plasmacytosis highlighted with CD138 staining in the interfollicular space is characteristic of plasma cell CD type (×200)