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Table 1 Renal outcome measures

From: Effect of large weight reductions on measured and estimated kidney function

Variable Baseline 6 months post-surgery Change from baseline (95% CI) p-value
mGFR (51Cr-EDTA), ml/min (absolute) 122 (24) 113 (21) −9 (−17; −2) 0.021
mGFR (51Cr-EDTA), ml/min/1.73 m2 (corrected for body surface area) 88 (17) 90 (16) 2 (−5; 9) 0.52
Body surface area, m2 2.38 (0.22) 2.14 (0.23) 0.24 (0.20; 0.28) <0.001
Plasma creatinine, μmol/l 76 (18) 66 (12) −9 (−14; −5) <0.001
Plasma cystatin C, mg/l 0.94 (0.19) 0.96 (0.19) 0.02 (−0.04; 0.07) 0.61
CKD-EPI-sCr eGFR, ml/min/1.73 m2 93 (18) 105 (15) 12 (6; 17) <0.001
MDRD eGFR, ml/min/1.73 m2 84 (21) 97 (22) 13 (8; 18) <0.001
CKD-EPI-cysC eGFR, ml/min/1.73 m2 89 (19) 87 (23) −2 (−8; 4) 0.51
CKD-EPI-sCr-cysC eGFR, ml/min/1.73 m2 91 (19) 96 (21) 5 (−3; 10) 0.074
24-h systolic blood pressure, mmHg 122 (14) 124 (13) 2 (−5; 10) 0.56
24-h diastolic blood pressure, mmHg 82 (10) 79 (11) −3 (−9; 4) 0.41
Urinary albumin-to-creatinine ratio, mg/g 6.3 (2.7–8.1) 4.8 (2.1–5.2) −23 (−35; −9) % 0.005
Extracellular volume, l 20.4 (5.9) 20.4 (6.3) 0 (−2.5; 2.6) 0.99
Plasma urea, mmol/l 5.0 (1.5) 4.3 (1.1) −0.7 (−1.3; −0.02) 0.043
Plasma calcium, mmol/l 1.28 (0.04) 1.28 (0.03) 0 (−0.02; 0.02) 0.74
  1. Values represent mean (SD) or geometric mean (IQR)
  2. GFR glomerular filtration rate