Table 3 Surfactant protein D gene polymorphisms in sepsis-induced AKI patients and healthy controls
Genotype/allele | Sepsis-induced AKI patients, n(%) | Controls, n(%) | Odds ratio (95% CI) | P value |
|---|---|---|---|---|
Met11Thr | ||||
Met/Met | 20 (22.5) | 51 (42.5) | 0.392 (0.212–0.726) | 0.003** |
Met/Thr | 40 (44.9) | 54 (45.0) | ||
Thr/Thr | 29 (32.6) | 15 (12.5) | 3.383 (1.681–6.810) | 0.001** |
Allele | ||||
Met | 80 (44.9) | 156 (65.0) | 0.440 (0.296–0.654) | |
Thr | 98 (55.1) | 84 (35.0) | 2.275 (1.529–3.384) | 0.001** |
Ala160Thr | ||||
Ala/Ala | 35 (39.3) | 49 (40.8) | 0.952 (0.544–1.666) | 0.888 |
Ala/Thr | 43 (48.3) | 52 (43.3) | ||
Thr/Thr | 11 (12.4) | 20 (15.9) | 0.712 (0.322–1.574) | 0.437 |
Allele | ||||
Ala | 113 (63.5) | 150 (62.5) | 1.043 (0.698–1.559) | |
Thr | 65 (36.5) | 90 (37.5) | 0.959 (0.642–1.433) | 0.919 |