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Table 2 Patient characteristics associated with lack of conversion to functional AV access in patients starting hemodialysis with nonfunctional AV access or with catheter only

From: Vascular access conversion and patient outcome after hemodialysis initiation with a nonfunctional arteriovenous access: a prospective registry-based study

Characteristics Vascular access at baseline P-value for interactiona
Nonfunctional AV access Catheter only
aOR (95% CI) P-value aOR (95% CI) P-value
Women 1.25 (1.10–1.43) 0.0009 1.28 (1.20–1.36) <0.0001 0.9514
Age (1-year increase) 1.01 (1.01–1.02) <0.0001 1.02 (1.01–1.02) <0.0001 0.0117
Primary renal disease   0.5615   <0.0001 0.0938
 Hypertensive/Vascular 0.94 (0.73–1.22)   0.93 (0.83–1.04)   
 Diabetic nephropathy 0.94 (0.71–1.25)   0.84 (0.74–0.95)   
 Glomerulonephritis      
 Polycystic kidney disease 1.11 (0.76–1.61)   0.79 (0.64–0.97)   
 Other 1.13 (0.87–1.47)   1.19 (1.07–1.33)   
 Unknown 1.00 (0.75–1.34)   1.15 (1.03–1.29)   
Diabetes 0.92 (0.77–1.10) 0.3405 0.99 (0.92–1.07) 0.8856 0.6441
Number of cardiovascular comorbidities 0.0008   <0.0001 0.4444
 0      
 1 1.19 (1.01–1.40)   1.12 (1.04–1.21)   
 2 1.27 (1.04–1.54)   1.39 (1.28–1.52)   
 3 1.45 (1.16–1.82)   1.58 (1.42–1.75)   
 4 or 5 2.09 (1.55–2.82)   1.88 (1.63–2.17)   
Lower limb amputation 1.13 (0.73–1.74) 0.5884 1.26 (1.07–1.47) 0.0050 0.3740
Malignancy 1.23 (0.99–1.52) 0.0592 1.65 (1.51–1.79) <0.0001 0.0056
Mobility status   <0.0001   <0.0001 0.0105
 Autonomous      
 Needs assistance 1.41 (1.17–1.69)   1.61 (1.48–1.74)   
 Totally dependent 2.05 (1.55–2.70)   2.90 (2.56–3.28)   
Body mass index (kg/m2) 0.9333   0.0003 0.0856
 <18.5 1.03 (0.73–1.47)   1.21 (1.07–1.36)   
 [18.5–25.0]      
 [25.0–30.0] 1.01 (0.86–1.19)   0.96 (0.89–1.03)   
 ≥30.0 1.03 (0.86–1.23)   0.85 (0.78–0.94)   
Serum albumin (1-g/l increase) 0.99 (0.98–1.01) 0.3773 0.99 (0.99–1.00) 0.0033 0.2750
Anemia (hemoglobin <10 g/dl) 0.95 (0.83–1.10) 0.5156 0.91 (0.85–0.97) 0.0027 0.6696
Predialysis ESA treatment 1.12 (0.98–1.27) 0.0899 1.04 (0.97–1.11) 0.3031 0.3383
Estimated glomerular filtration rate (MDRD ml/min/1.73 m2) 0.0037   <0.0001 0.9829
 eGFR≤5 0.68 (0.54–0.86)   0.75 (0.68–0.83)   
 5<eGFR≤10 0.88 (0.74–1.03)   0.91 (0.84–0.99)   
 10<eGFR≤15      
 15<eGFR≤20 1.11 (0.83–1.48)   1.19 (1.04–1.37)   
 eGFR>20 1.38 (0.90–2.12)   1.35 (1.13–1.60)   
Facility type   0.0001   0.0001 0.3805
 In center      
 Satellite unit 0.37 (0.19–0.73)   0.59 (0.42–0.82)   
 Self-dialysis 0.28 (0.14–0.57)   0.48 (0.35–0.65)   
Facility ownership   0.0790   0.1452 0.6509
 Public university      
 Public non-university 0.77 (0.66–0.91)   0.82 (0.76–0.89)   
 Private for-profit 0.78 (0.66–0.92)   0.79 (0.73–0.85)   
 Private not-for-profit 1.11 (0.88–1.40)   0.94 (0.85–1.05)   
  1. a P-value for interaction between patient characteristic and AV access at baseline. ORs were adjusted for year of hemodialysis initiation and for all variables in Table 2. Abbreviations: aOR adjusted odds ratio, CI confidence interval, AV arteriovenous, ref reference, ESA erythropoiesis-stimulating agents, MDRD Modification of Diet in Renal Disease