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Table 3 Linear regression analysis of the association between TGF-β quartiles and eGFR and urinary ACR

From: Higher plasma transforming growth factor (TGF)-β is associated with kidney disease in older community dwelling adults

 

Quartile 1

β estimate (95% CI)

Quartile 2

β estimate (95% CI)

Quartile 3

β estimate (95% CI)

Quartile 4

β estimate (95% CI)

eGFR

M0

REF

–4.55 (–7.14,–1.95)

–4.92 (–7.52,–2.32)

–4.47 (–7.07,–1.88)

M1

REF

–3.8 (–6.26,–1.34)

–4.02 (–6.48,–1.56)

–4.36 (–6.83,–1.89)

M2

REF

–4.57 (–7,–2.14)

–4.68 (–7.09,–2.27)

–3.86 (–6.28,–1.44)

Urinary ACR

M0

REF

0.24 (–0.02,0.5)

0.21 (–0.06,0.47)

0.25 (–0.01,0.51)

M1

REF

0.21 (–0.05,0.47)

0.16 (–0.1,0.42)

0.18 (–0.08,0.44)

M2

REF

0.25 (0,0.5)

0.20 (–0.05,0.45)

0.15 (–0.1,0.4)

  1. M0: unadjusted analysis
  2. M1: M0 + age, male gender, and black race
  3. M2: M1 + current smoking status, hypertension, diabetes mellitus, body mass index, LDL-cholesterol, triglycerides, history of cardiovascular disease, and C-reactive protein