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Table 2 Clinical parameters, laboratory findings, and management characteristics among 258 adults with snakebite envenomation, Yangon, Myanmar, 2015–2016

From: Clinical and laboratory parameters associated with acute kidney injury in patients with snakebite envenomation: a prospective observational study from Myanmar

Characteristics

All

With acute kidney injury, n (%)

Without acute kidney injury, n (%)

p value

Clinical parameters

    

Bites from Viperidae or presenting the clinical syndrome of Viperidae

    

 Yes

214

136 (63.6)

78 (36.4)

<0.001

 No

44

4 (9.1)

40 (90.9)

 

Local swelling

    

 Grades II–IV

167

111 (66.5)

56 (33.5)

<0.001

 Grades 0-I

91

29 (31.9)

62 (68.1)

 

Hypotension

    

 Yes

69

60 (87.0)

9 (13.0)

<0.001

 No

189

80 (42.3)

109 (57.7)

 

Laboratory parameters

    

WBC (cells/μL)

    

  > 10 × 103

194

126 (64.9)

68 (35.1)

<0.001

  ≤ 10 × 103

64

14 (21.9)

50 (78.1)

 

Overt DIC

    

 Yes

147

103 (70.1)

44 (29.9)

<0.001

 No

111

37 (33.3)

74 (66.7)

 

Capillary leakage

    

 Yes

35

30 (85.7)

5 (14.3)

<0.001

 No

223

110 (49.3)

113 (50.7)

 

Creatine kinase (IU/L)

    

  > 500

104

87 (83.7)

17 (16.3)

<0.001

  ≤ 500

152

51 (33.6)

101 (66.4)

 

Blood sugar (mg/dL)

    

  ≥ 150

53

37 (69.8)

16 (30.2)

0.017

  < 150

205

103 (50.2)

102 (49.8)

 

Serum sodium (mmol/L)

    

  < 135 mmol/L

115

91 (79.1)

24 (20.9)

<0.001

  ≥ 135 mmol/L

143

49 (34.3)

94 (65.7)

 

Microscopic hematuria

    

 Yes

81

70 (86.4)

11 (13.6)

<0.001

 No

174

67 (38.5)

107 (61.5)

 

Management

    

Site of management

    

 Ward

211

129 (61.1)

82 (38.9)

<0.001

 ICU

47

11 (23.4)

36 (76.6)

 

Time from bite to receiving antivenom (hours)

    

  ≥ 2

174

107 (61.5)

67 (38.5)

0.007

  < 2

76

32 (42.1)

44 (57.9)

 
  1. Abbreviations: DIC disseminated intravascular coagulation, ICU intensive care unit, WBC white blood cell, 20WBCT 20-min whole blood clotting test