Targets for adapting intravenous iron dose in hemodialysis: a proof of concept study

BMC Nephrology

Table 1 Clinical practice guidelines for anemia management in chronic kidney disease according to transferring saturation, serum ferritin and upper limit of serum ferritin for iron supplementation

Guidelines		TSAT(%)	Serum ferritin (μg/L)	Upper limit of serum ferritin (μg/L)
KDOQI 2006 [16]		<20	<100	500
CSN 2008 [18]	HD	<20	<200	None
	PD/ND	<20	<100	None
JSDT 2008 [11]		<20	<100	500
ERBP 2009 [17]		<20	<100	500
KDIGO 2012 [7]		<30	<500	500 (or TSAT > 30%)
CSN 2012 [10]		<30	<500	None
ERBP 2013 [8]	No ESA/no anemia	<20	<100	500
	No ESA/anemia/ND	<25	<200	500
	No ESA/anemia/HD or PD	<25	<300	500
	ESA/anemia/on dialysis	<30	<300	500
KDOQI 2013 [9]		<30	<500	None
NICE 2015 [12]		<20	<100	800

KDOQI Kidney Disease Outcomes Quality Initiative, CSN Canadian Society of Nephrology, JSDT Japanese Society of Dialysis Therapy, KDIGO Kidney Disease Improving Global Outcomes, ERBP European Renal Best Practice, NICE National Institute for Health and Care Excellence, HD on hemodialysis, PD peritoneal dialysis, ND not on dialysis, ESA erythropoiesis-stimulating agent, TSAT transferrin saturation

ISSN: 1471-2369