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Table 5 Comparisons of clinical characteristics according to disease progression in patients with subnephrotic range proteinuria

From: Factors affecting the long-term outcomes of idiopathic membranous nephropathy

 

Progression to NS (N = 26)

No progressiona (N = 39)

P-value

Male

9 (34.6%)

23 (58.9%)

0.124

Age (years)

53 ± 11

47 ± 13

0.088

BMI (kg/m2)

23.5 ± 2.3

23.9 ± 2.8

0.513

Hypertension

8 (28.6%)

8 (20.5%)

0.558

Serum creatinine (mg/dl)

0.90 ± 0.18

1.11 ± 0.80

0.230

Serum albumin (g/dl)

2.67 ± 0.61

3.36 ± 0.48

<0.001

Serum cholesterol (mg/dl)

274.1 ± 92.4

225.3 ± 62.4

0.018

CKD stage according to eGFR

0.399

 Stage I

14 (53.8%)

14 (35.9%)

 

 Stage II

10 (38.5%)

18 (46.1%)

 

 Stage III

1

4 (10.3%)

 

 Stage IV-V

1

3 (7.7%)

 

Serum hemoglobin (g/dL)

12.4 ± 2.2

13.4 ± 1.9

0.073

Proteinuria (g/g creatinine)

2.46 ± 0.73

1.83 ± 0.92

0.005

  1. Data are presented as number (% of total) or means ± SD
  2. BMI Body mass index, CKD Chronic kidney disease, eGFR estimated glomerular filtration rate, estimated with Modification of Diet in Renal Disease, NS nephrotic syndrome
  3. aGroup of ‘No progression’ include patients that had spontaneous remission or remission through immunosuppressant or stable status of disease