Fig. 3
From: Nephrotoxicity-induced proteinuria increases biomarker diagnostic thresholds in acute kidney injury
Sensitivity and specificity of 95th centile values of structural biomarker values from healthy volunteers in detecting functional-AKI or death. Serum creatinine ≥ 100% (AKI ≥ 2) is defined as functional-AKI while biomarker concentration >95th centile value in healthy volunteers (uCysC: 70 ng/mg Cr; uClu: 420 ng/mg Cr; uKIM-1 1.2 ng/mg Cr; uβ2M 166 ng/mg Cr and uNGAL: 120 ng/mg Cr) were used to define structural-AKI. Grey and black area on the chart depicts 'Albuminuria' and 'No albuminuria' respectively