Fig. 1From: Ultrastructural deposits appearing as “zebra bodies” in renal biopsy: Fabry disease?– comparative case reportsElectron microscopy: Case 1 - first biopsy (a and b): intralysosomal, osmiophilic, lamellated and sometimes concentric inclusions in the cytoplasm of podocytes (black arrows) resembling or “zebra bodies”. Case 1 – second biopsy (c, d and e): podocytes presented cytoplasmatic swelling (arrow heads), sometimes forming optically empty vacuoles (slim black arrows) and there are some podocyte foot process effacement (white arrows). The lipid deposits seen in the previous biopsy were no longer detected. Case 2 - (f, g and h): deposits of lamellate, lipid-like, electron-dense material forming concentric bodies, “zebra bodies” in the cytoplasm of podocytes (black arrows) (f, h) and endothelial cells in both glomerular (white arrow head) (f) and peritubular capillaries (white slim arrows) (g).Image magnifications are specified in each lower borderBack to article page