Periodontitis and early mortality among adults treated with hemodialysis: a multinational propensity-matched cohort study

Table 3 Mortality outcomes with moderate to severe periodontitis among the whole cohort, propensity-weighted analyses and propensity-score matched patients with end-stage kidney disease treated with hemodialysis

		No (events per 100 person years)
	Number of participants included in analyses	Moderate to severe periodontitis	No or mild periodontitis	Hazard ratio (95% CI)*
All-cause mortality
Whole cohort	3338	242 (9.1)	408 (11.7)	0.94 (0.73 to 1.21)
Propensity-weighted	3338	242 (9.1)	408 (11.7)	0.83 (0.68 to 1.00)
Propensity-matched	2710	242 (9.1)	314 (13.0)	0.74 (0.61 to 0.90)
Cardiovascular mortality
Whole cohort	3338	113 (4.3)	212 (6.1)	0.91 (0.64 to 1.29)
Propensity-weighted	3338	113 (4.3)	212 (6.1)	0.76 (0.58 to 1.00)
Propensity-matched	2710	113 (4.3)	167 (6.9)	0.67 (0.51 to 0.88)

Hazard ratios are reported for moderate to severe periodontitis (no or mild periodontitis is the reference group). CI denotes confidence interval. *Hazard ratios are controlled for age, sex, income, smoking, serum phosphorus, myocardial infarction, diabetes mellitus, mean arterial pressure, time on dialysis and number of teeth using a Cox proportional hazards regression model. Clustering by country was accounted for by random effects Cox proportional hazards regression fitted using a shared frailty model

ISSN: 1471-2369