Fig. 4From: The effect of disease severity markers on quality of life in autosomal dominant polycystic kidney disease: a systematic review, meta-analysis and meta-regressionMeta-regression analysis of the physical component score of the SF-36 with the factors (a) (e)GFR (ml/min/1.73m2) and b Kidney volume after exclusion of studies with severe liver involvement. Volumes are presented on a logarithmic scale. Barros et al., [34]; Lee et al., [37]; Miskulin et al., [13] subgroup eGFR 20–44*; Miskulin et al., [13] subgroup eGFR 45–60; Miskulin et al., [13] subgroup eGFR ≥60; Rizk et al., [16]; Simms et al., [38] subgroup eGFR <30; Simms et al., [38] subgroup eGFR 30–60; Simms et al., [38] subgroup eGFR >60. *No kidney and liver imaging in this subgroup, not included in figure b Back to article page