Timing of commencement of maintenance dialysis and mortality in young and older adults in Singapore

BMC Nephrology

Table 4 ^aAdjusted hazard ratios (HR) associated with eGFR at initial dialysis stratified by age groups

Age group	eGFR Category (ml/min/1.73m²)	Number of overall patients	Number (incidence %) of death	HR (95% CI)	ǂP value HR	ǂP value Trend
18 to 54 years	Late (<5)	495	69 (13.9)	1.00
	Intermediate (5–10)	249	65 (26.1)	1.57 (1.10–2.24)	0.013	0.006
	Early (≥10)	28	9 (32.1)	1.95 (0.95–4.03)	0.070
55 to 64 years	Late (<5)	426	100 (23.5)	1.00		<0.001
	Intermediate (5–10)	346	120 (34.7)	1.46 (1.10–1.92)	0.008
	Early (≥10)	39	20 (51.3)	3.30 (1.99–5.47)	<0.001
≥65 years	Late (<5)	474	190 (40.1)	1.00		0.12
	Intermediate (5–10)	423	198 (46.8)	1.12 (0.91–1.39)	0.29
	Early (≥10)	60	32 (53.3)	1.36 (0.90–2.04)	0.14

P value for interaction between eGFR and age in adjusted model was 0.038
^aAdjusted for age, gender, ethnicity, education, smoking, diabetes, hypertension, cerebrovascular disease, ischemic heart disease, peripheral vascular disease, malignancy, Hepatitis B Ag, Anti-Hepatitis C, modality of dialysis, albumin.
ǂP values were derived from Wald test.

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