Fig. 3

Illustration of fluid-related weight gain calculation for a single representative patient with varying observed IDWGs and UF rates over 12 consecutive treatments.The light gray circles and corresponding dashed lines represent the prescribed UF rates on the basis of observed IDWGs and prescribed TTs without application of a UF rate threshold across the study month. The horizontal dashed reference line represents a UF rate of 13 ml/h/kg. For treatments with prescribed UF rates ≥13 mL/h/kg, the black bars represent the calculated amount of fluid-related weight that would be gained if a UF rate threshold of 13 mL/h/kg was applied. For treatments with prescribed UF rates <13 mL/h/kg, the gray bars represent the calculated amount of fluid-related weight that would be lost (from prior fluid-related weight gains) if the UF rate was allowed to rise to a level of 13 mL/h/kg. Detailed methods and an example of the 1-month cumulative fluid-related weight gain computation are provided in Additional file 1: Table S2. Abbreviations: IDWG, interdialytic weight gain; TT, treatment time; UF, ultrafiltration