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Table 3 Bivariate regression analysis between patients with baseline dp-ucMGP <1000 and those >1000 pM

From: High Dephosphorylated-Uncarboxylated MGP in Hemodialysis patients: risk factors and response to vitamin K2, A pre-post intervention clinical trial

 

Baseline dp-ucMGP <1000 N = 5

Baseline dp-ucMGP >1000 N = 45

P-value

Age (years), median (IQR)

55.0 (38.0; 64.0)

73.0 (61.0; 80.0)

0.02

Gender, male n (%)

3 (60.0)

27 (60.0)

1.00

Dialysis vintage (months), median (IQR)

36.0 (9.5; 152.0)

47.0 (28.5; 108.5)

0.73

Diabetes, n (%)

2 (40.0)

16 (35.6)

1.00

Hypertension, n (%)

3 (60.0)

35 (77.8)

0.58

Smoking, n (%)

0 (0.0)

8 (17.8)

0.58

Calcification score, median (IQR)

1.0 (0.5; 5.5)

8.0 (2.0; 14.0)

0.02

NCBB, n (%)

2 (40.0)

18 (40.0)

1.00

Residual diuresis, n (%)

0 (0.0)

6 (13.3)

1.00

Calcium dose (tablets of 600 mg), median (IQR)

3.0 (1.5; 3.0)

1.0 (1.0; 2.0)

0.04

Alfacalcidol dose (μg), median (IQR)

0.75 (0.25; 1.87)

0.75 (0.00; 1.50)

0.90

Serum phosphate (mg/dl), median (IQR)

3.9 (3.6; 6.6)

3.9 (3.0; 4.6)

0.29

Serum calcium (mg/dl), median (IQR)

9.3 (9.05; 9.65)

9.1 (8.8; 9.2)

0.09

PTH (pg/ml), median (IQR)

127.0 (82.5; 297.0)

196.0 (118.0; 270.0)

0.29

LDL cholesterol (mg/dl), median (IQR)

80.0 (72.0; 113.0)

93.0 (77.0; 113.0)

0.59

BMI (Kg/m2), median (IQR)

30.2 (17.9; 34.3)

25.8 (22.9; 27.8)

0.69

URR, median (IQR)

71.0 (65.0; 81.5)

75.0 (72.0; 79.0)

0.46

Albumin, median (IQR)

40.0 (35.5; 44.5)

39.0 (36.0; 41.0)

0.44

CAD, n (%)

1 (20.0)

13 (28.9)

1.00

Cinacalcet, n (%)

0 (0.0)

2 (4.4)

1.00

Previous acenocoumadin, n (%)

2 (40.0)

4 (8.9)

0.10

PTHX, n (%)

0 (0.0)

2 (4.4)

1.00

Recent fracture, n (%)

0 (0.0)

3 (6.7)

1.00

  1. Abbreviations: NCBB non-calcium-based phosphate binders, PTH intact parathyroid hormone, BMI body mass index, URR urea reduction ratio, CAD documented coronary artery disease, PTHX previous parathyroidectomy