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Table 3 Bivariate regression analysis between patients with baseline dp-ucMGP <1000 and those >1000 pM

From: High Dephosphorylated-Uncarboxylated MGP in Hemodialysis patients: risk factors and response to vitamin K2, A pre-post intervention clinical trial

  Baseline dp-ucMGP <1000 N = 5 Baseline dp-ucMGP >1000 N = 45 P-value
Age (years), median (IQR) 55.0 (38.0; 64.0) 73.0 (61.0; 80.0) 0.02
Gender, male n (%) 3 (60.0) 27 (60.0) 1.00
Dialysis vintage (months), median (IQR) 36.0 (9.5; 152.0) 47.0 (28.5; 108.5) 0.73
Diabetes, n (%) 2 (40.0) 16 (35.6) 1.00
Hypertension, n (%) 3 (60.0) 35 (77.8) 0.58
Smoking, n (%) 0 (0.0) 8 (17.8) 0.58
Calcification score, median (IQR) 1.0 (0.5; 5.5) 8.0 (2.0; 14.0) 0.02
NCBB, n (%) 2 (40.0) 18 (40.0) 1.00
Residual diuresis, n (%) 0 (0.0) 6 (13.3) 1.00
Calcium dose (tablets of 600 mg), median (IQR) 3.0 (1.5; 3.0) 1.0 (1.0; 2.0) 0.04
Alfacalcidol dose (μg), median (IQR) 0.75 (0.25; 1.87) 0.75 (0.00; 1.50) 0.90
Serum phosphate (mg/dl), median (IQR) 3.9 (3.6; 6.6) 3.9 (3.0; 4.6) 0.29
Serum calcium (mg/dl), median (IQR) 9.3 (9.05; 9.65) 9.1 (8.8; 9.2) 0.09
PTH (pg/ml), median (IQR) 127.0 (82.5; 297.0) 196.0 (118.0; 270.0) 0.29
LDL cholesterol (mg/dl), median (IQR) 80.0 (72.0; 113.0) 93.0 (77.0; 113.0) 0.59
BMI (Kg/m2), median (IQR) 30.2 (17.9; 34.3) 25.8 (22.9; 27.8) 0.69
URR, median (IQR) 71.0 (65.0; 81.5) 75.0 (72.0; 79.0) 0.46
Albumin, median (IQR) 40.0 (35.5; 44.5) 39.0 (36.0; 41.0) 0.44
CAD, n (%) 1 (20.0) 13 (28.9) 1.00
Cinacalcet, n (%) 0 (0.0) 2 (4.4) 1.00
Previous acenocoumadin, n (%) 2 (40.0) 4 (8.9) 0.10
PTHX, n (%) 0 (0.0) 2 (4.4) 1.00
Recent fracture, n (%) 0 (0.0) 3 (6.7) 1.00
  1. Abbreviations: NCBB non-calcium-based phosphate binders, PTH intact parathyroid hormone, BMI body mass index, URR urea reduction ratio, CAD documented coronary artery disease, PTHX previous parathyroidectomy