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Table 5 Specificity (Sp), Sensitivity (Sn) and cutoff values of target biomarkers for CKDu cases against non-endemic and endemic controls

From: Screening for chronic kidney disease of uncertain aetiology in Sri Lanka: usability of surrogate biomarkers over dipstick proteinuria

  CKDu against non-endemic control CKDu against endemic control
Cutoffa Sn Sp Cutoffa Sn Sp
S.Cr 89 0.84 0.88 111.5 0.57 0.88
S.Cys 1.01 0.89 0.80 1.22 0.75 0.84
ACR 6.06 0.70 0.64 12.66 0.54 0.82
Dipstick proteinuriab      0.4 0.8
  1. aCutoff values in same units as in Table 3
  2. bdipstick proteinuria (≥1+ and including trace)