C-terminal fragment of agrin (CAF) levels predict acute kidney injury after acute myocardial infarction

BMC Nephrology

Table 2 Discriminating ability (area under the curve) of the under investigation variables regarding the incidence of AKI during hospitalization

	AUC	95% CI	P value	Sens	Spec	+PV	-PV
Urine
IL-18	0.538	0.450-0.626	0.35
NGAL	0.616	0.540-0.692	0.004	75	45	19	91
Cyst-C	0.573	0.489-0.657	0.07
CAF	0.630	0.552-0.708	0.001	37	85	30	89
Plasma
IL-18	0.530	0.440-0.619	0.47
NGAL	0.522	0.438-0.606	0.6
Cyst-C	0.571	0.492-0.650	0.08
CAF	0.587	0.509-0.666	0.03	71	47	19	90

AKI acute kidney injury, AUC area under the curve, CAF C-terminal agrin fragment, CI confidence interval, Cyst-C cystatin-C, IL-18 interleukin-18, NGAL neutrophil gelatinase-associated lipocalin, n/a non-applicable, Sens sensitivity, Spec specificity, +PV positive predictive value, −PV negative predictive value

ISSN: 1471-2369