Skip to main content

Table 4 Binary Logistic Regression analysis of five models assessing for collinearity as described in the text

From: Deviations from the expected relationship between serum FGF23 and other markers in children with CKD: a cross-sectional study

MODEL 1. Condition: FGF23 > 230 pg/mL

In the presence of: Phosphate, 1,25 (OH)2 Vit D, PTH and CKD Stage.

Parameter

SE

OR (CI 95%)

p

Phosphate [mmol/L]

Below 1.60

0.948

0.056

(0.009–0.357)

0.002*

1,25 (OH)2 Vit D [pmol/L]

Over 50

1.033

0.400

(0.053–3.028)

0.375

PTH [pmol/L]

0.016

1.000

(0.969–1.032)

0.968

CKD Stage Cystatin C eGFR [mL/min/1.73 m2]

0.483

2.940

(1.141–7.575)

0.026*

MODEL 2. Condition: FGF23 > 230 pg/mL

In the presence of: Bicarbonate, 1,25 (OH)2 Vit D, PTH and Ionized Calcium.

Parameter

SE

OR (CI 95%)

p

Bicarbonate [mmol/L]

0.107

0.936

(0.760–1.154)

0.536

1,25 (OH)2 Vit D [pmol/L]

Over 50

0.850

0.138

(0.026–0.728)

0.020*

PTH [pmol/L]

0.014

1.026

(0.998–1.053)

0.066

Ionized Calcium

[mmol/L]

4.753

0.002

(0.000–23.520)

0.195

MODEL 3. Condition: FGF23 > 230 pg/mL

In the presence of: 1,25 (OH)2 Vit D, PTH, Ionized Calcium and Phosphate.

Parameter

SE

OR (CI 95%)

p

1,25 (OH)2 Vit D [pmol/L]

Over 50

0.975

0.100

(0.015–0.673)

0.018*

PTH [pmol/L]

0.016

1.014

(0.983–1.047)

0.379

Ionized Calcium

[mmol/L]

4.431

7.980

(0.001–467.56)

0.641

Phosphate [mmol/L]

Below 1.60

0.923

0.045

(0.007–0.277)

0.001*

MODEL 4. Condition: FGF23 > 230 pg/mL

In the presence of: Bicarbonate, CRP, 1,25 (OH)2 Vit D and PTH.

Parameter

SE

OR (CI 95%)

p

Bicarbonate [mmol/L]

0.082

1.021

(0.868–1.200)

0.804

CRP

0.038

0.987

(0.917–1.063)

0.735

1,25 (OH)2 Vit D [pmol/L]

Over 50

0.788

0.110

(0.024–0.517)

0.005*

PTH [pmol/L]

0.014

1.027

(1.000–1.055)

0.053

MODEL 5. Condition: pH > 7.35

In the presence of: FGF23, Ionized Calcium, Bicarbonate and CKD Stage.

Parameter

SE

OR (CI 95%)

p

FGF23 [pg/mL]

0.005

1.009

(1.000–1.019)

0.047*

Ionized Calcium

[mmol/L]

3.325

0.028

(0.000–18.791)

0.281

Bicarbonate [mmol/L]

0.064

0.913

(0.806–1.035)

0.155

CKD Stage Cystatin C eGFR [mL/min/1.73 m2]

0.252

0.588

(0.359–0.964)

0.035*

  1. *denotes significant associations (p < 0.05)
  2. SE Standard error, OR Odds ratio, CI Confident interval. For a significant p value <0.05
Back to article page

BMC Nephrology

ISSN: 1471-2369

Contact us