Blood volume-monitored regulation of ultrafiltration to decrease the dry weight in fluid-overloaded hemodialysis patients: a randomized controlled trial

Table 3 Group-wise dry weight reduction

				p-value⁺
	CONV	UTR	UCR	CONV vs UTR	CONV vs UCR	UTR vs UCR	Overall
N participants with dry weight reduction	12	17	14
Initial Dry Weight [kg]	75.6 ± 26.2	67.6 ± 11.9	66.9 ± 16.6				0.44
Ideal Dry Weight [kg] (=Normohydration Weight - 7% ECV)	70.3 ± 25.6	63.2 ± 11.2	62.9 ± 16.0				0.49
Diff. from Initial Dry Weight [kg]	−5.3 ± 1.8	−4.3 ± 1.8	−4.0 ± 2.0				0.27
[% Body Weight]	−7.4 ± 2.2	−6.4 ± 2.3	−5.7 ± 2.7				0.22
Dry Weight Reached [kg]	72.6 ± 25.3	64.1 ± 10.7	65.4 ± 16.6				0.42
Diff. from Initial Dry Weight [kg]	−3.0 ± 1.9	−3.5 ± 2.8	−1.5 ± 1.9	0.30	0.15	0.010	0.036
[% Body Weight]	−3.9 ± 2.1	−5.0 ± 3.4	−2.0 ± 2.7	0.31	0.06	0.013	0.022
Ideal Dry Weight Missed by … [kg]	2.3 ± 1.8	0.8 ± 2.1	2.5 ± 1.8	0.06	0.87	0.031	0.044
[% Body Weight]	3.5 ± 2.7	1.4 ± 3.2	3.7 ± 2.4				0.06

CONV conventional hemodialysis, UTR ultrafiltration and temperature regulation, UCR ultrafiltration and dialysate conductivity regulation, N number, ECV extracellular volume, SBP systolic blood pressure, DBP diastolic blood pressure, BCM body composition monitor
PP analysis. ⁺ P-values between groups determined by two-tailed t-test, and Mann-Whitney U test. Overall p-values determined by analysis of variance and analysis of covariance (for comparison of repeated measures). In one patient from the UTR group only absolute fluid overload values could be measured; relative fluid overload values could not be calculated by the BCM device due to technical issues, resulting in deviation of the FO value from ECV

ISSN: 1471-2369