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Fig. 3 | BMC Nephrology

Fig. 3

From: Serum lactate level and mortality in metformin-associated lactic acidosis requiring renal replacement therapy: a systematic review of case reports and case series

Fig. 3

Odds ratio for metformin-associated lactic acidosis (MALA) mortality by serum lactate level in this systematic review. Solid lines represent adjusted odds ratios based on restricted quadratic splines for the serum lactate level, with knots at the 10th, 50th, and 90th percentiles. The shaded green region represent upper and lower 95% CIs. The reference value was set at 10th percentile. Adjustment factors were the same as those in Table 3. The bars represent a histogram of serum lactate distribution among enrolled cases (the extreme tails of the histogram were truncated)

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BMC Nephrology

ISSN: 1471-2369

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