Table 2 Etiologic factors underlying development of rhabdomyolysis in the total HIV cohort and according to viral loada
From: Rhabdomyolysis in an HIV cohort: epidemiology, causes and outcomes
Etiology | Overall (n = 362) | Viral load <400 copies/ml (n = 71) | Viral Load ≥400 copies/ml (n = 291) | p-value |
|---|---|---|---|---|
Infection | 141 (39%) | 17 (24%) | 124 (43%) | 0.004 |
Pneumonia | 75 (21%) | 7 (10%) | 68 (23%) | |
Bacteremia | 26 (7%) | 4 (6%) | 22 (8%) | |
Viral Illness | 25 (7%) | 3 (4%) | 22 (8%) | |
Pyelonephritis | 8 | 2 | 6 | |
Endocarditis | 7 | 0 | 7 | |
Fungemia | 7 | 2 | 5 | |
Acute antiretroviral illness | 6 | 0 | 6 | |
Abscess | 6 | 1 | 5 | |
Line Infection | 5 | 1 | 4 | |
Necrotizing Fasciitis | 5 | 0 | 5 | |
Sinusitis | 5 | 1 | 4 | |
Meningitis | 4 | 0 | 4 | |
Othersb | 12 | 2 | 10 | |
Trauma/compression | 82 (23%) | 25% | 22% | 0.544 |
Cocaine | 76 (21%) | 11% | 23% | 0.025 |
Seizure | 26 (7%) | 7% | 7% | 0.959 |
Alcohol | 24 (6.6%) | 6% | 7% | 0.707 |
Medications | 22 (6%) | 17% | 4% | <0.001 |
Cardiopulmonary arrest | 20 (6%) | 6% | 6% | 0.964 |
Surgery | 16 | 6% | 4% | 0.579 |
Hypokalemia | 12 | 4% | 3% | 0.633 |
HIV Associated Myositis | 11 | 1% | 3% | 0.372 |
Physical Exertion | 8 | 1% | 2% | 0.608 |
Ischemic Limb | 8 | 4% | 2% | 0.198 |
Hypothyroidism | 2 | 1% | 1% | 0.484 |
Unclear | 25 (7%) | 13% | 6% | 0.032 |
Miscellaneous | 25 (7%) | 10% | 6% | 0.470 |