A comparison of early versus late initiation of renal replacement therapy for acute kidney injury in critically ill patients: an updated systematic review and meta-analysis of randomized controlled trials

Table 1 The Basic Characteristics of Studies Included in Meta-analysis

Author	Year	Country	Study Period	Study design	Population	Duration of Follow-up (days)	No. of Patients			Mean Age (year)		Male (%)
Author	Year	Country	Study Period	Study design	Population	Duration of Follow-up (days)	Total	Early	Late	Early	Late	Early	Late
Bouman	2002	Netherlands	1998–2000	Two center	Cardiac surgery/surgical/medical	28	106	70	36	EHV:68 ELV:70	LLV:67	EHV:60 ELV:57	LLV:61
Durmaz	2003	Turkey	1999–2001	Single-center	Cardiac Surgery	30	44	21	23	58	54	76	83
Sugahara	2004	Japan	1995–1997	Single-center	Cardiac Surgery	14	28	14	14	65	64	64	64
Payen	2009	France	1997–2000	Multicenter	Medical/surgical	28	76	37	39	58	59	73	69
Jamale	2013	India	2010–2012	Single-center	Medical	90	208	102	106	43	42	61	75
Combes	2015	France	2009–2012	Multicenter	Cardiac Surgery	90	224	112	112	61	58	79	80
Wald	2015	Canada	2012–2013	Multicenter	Medical/surgical	90	100	48	52	62	64	73	71
Gaudry	2016	France	2013–2016	Multicenter	Medical/surgical	60	619	311	308	65	67	67	64
Zarbock	2016	Germany	2013–2015	Single-center	Cardiac surgery/surgical	90	231	112	119	66	68	70	57

Abbreviations: EHV early high volume, ELV early low volume, LLV late low volume

ISSN: 1471-2369