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Table 1 The Basic Characteristics of Studies Included in Meta-analysis

From: A comparison of early versus late initiation of renal replacement therapy for acute kidney injury in critically ill patients: an updated systematic review and meta-analysis of randomized controlled trials

Author Year Country Study Period Study design Population Duration of Follow-up (days) No. of Patients Mean Age (year) Male (%)
Total Early Late Early Late Early Late
Bouman 2002 Netherlands 1998–2000 Two center Cardiac surgery/surgical/medical 28 106 70 36 EHV:68
ELV:70
LLV:67 EHV:60
ELV:57
LLV:61
Durmaz 2003 Turkey 1999–2001 Single-center Cardiac Surgery 30 44 21 23 58 54 76 83
Sugahara 2004 Japan 1995–1997 Single-center Cardiac Surgery 14 28 14 14 65 64 64 64
Payen 2009 France 1997–2000 Multicenter Medical/surgical 28 76 37 39 58 59 73 69
Jamale 2013 India 2010–2012 Single-center Medical 90 208 102 106 43 42 61 75
Combes 2015 France 2009–2012 Multicenter Cardiac Surgery 90 224 112 112 61 58 79 80
Wald 2015 Canada 2012–2013 Multicenter Medical/surgical 90 100 48 52 62 64 73 71
Gaudry 2016 France 2013–2016 Multicenter Medical/surgical 60 619 311 308 65 67 67 64
Zarbock 2016 Germany 2013–2015 Single-center Cardiac surgery/surgical 90 231 112 119 66 68 70 57
  1. Abbreviations: EHV early high volume, ELV early low volume, LLV late low volume