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Table 3 Performance of new and existing end stage renal disease risk models in validation cohort for predicting 5-year risk of end stage renal disease

From: Prediction of new onset of end stage renal disease in Chinese patients with type 2 diabetes mellitus – a population-based retrospective cohort study

Validation statistics New model ADVANCE model New Zealand model
Male
 Harrell’s C statistic 0.866 (0.849,0.882) 0.858 (0.840,0.876) 0.863 (0.846,0.880)
 Difference in Harrell’s C statistic in comparison with new model - 0.008 0.002
 D statistic 2.458 (2.298,2.595) 2.429 (2.270,2.577) 2.482 (2.337,2.615)
 R2 59.1 (55.9,61.7) 58.5 (55.1,61.6) 59.5 (56.6,62.2)
Female
 Harrell’s C statistic 0.862 (0.845,0.880) 0.844 (0.822,0.865) 0.861 (0.842,0.880)
 Difference in Harrell’s C statistic in comparison with new model - 0.019* 0.001
 D statistic 2.410 (2.228,2.563) 2.366 (2.201,2.531) 2.493 (2.317,2.655)
 R2 58.1 (54.4,61.2) 57.2 (53.1,61.2) 59.7 (56.1,63.1)
  1. The brackets represented 95% confidence interval of corresponding validation statistic
  2. * Significant difference in Harrell’s C statistic (P-value <0.05)