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Table 3 Performance of new and existing end stage renal disease risk models in validation cohort for predicting 5-year risk of end stage renal disease

From: Prediction of new onset of end stage renal disease in Chinese patients with type 2 diabetes mellitus – a population-based retrospective cohort study

Validation statistics

New model

ADVANCE model

New Zealand model

Male

 Harrell’s C statistic

0.866 (0.849,0.882)

0.858 (0.840,0.876)

0.863 (0.846,0.880)

 Difference in Harrell’s C statistic in comparison with new model

-

0.008

0.002

 D statistic

2.458 (2.298,2.595)

2.429 (2.270,2.577)

2.482 (2.337,2.615)

 R2

59.1 (55.9,61.7)

58.5 (55.1,61.6)

59.5 (56.6,62.2)

Female

 Harrell’s C statistic

0.862 (0.845,0.880)

0.844 (0.822,0.865)

0.861 (0.842,0.880)

 Difference in Harrell’s C statistic in comparison with new model

-

0.019*

0.001

 D statistic

2.410 (2.228,2.563)

2.366 (2.201,2.531)

2.493 (2.317,2.655)

 R2

58.1 (54.4,61.2)

57.2 (53.1,61.2)

59.7 (56.1,63.1)

  1. The brackets represented 95% confidence interval of corresponding validation statistic
  2. * Significant difference in Harrell’s C statistic (P-value <0.05)